Biotics Research Bio-3B-G 180 tabs

Biotics Research's Bio-3B-G provides three times the RDA of the thiamin and 100% of the RDA of the B vitamin group, including B2, B3, B6 and B12, all in the phosphorylated forms. As such, it is similar in nature to the product Bio-B-100™ with the above noted increase in thiamin. 

The Importance of Phosphorylated B Vitamins

Bio-3B-G® provides biochemically activate forms of the B vitamins, including riboflavin 5- phosphate and cocarboxylase, in lieu of riboflavin and thiamin, respectively. Consequently, fewer enzymatic steps are needed to achieve a fully functional coenzyme. As an example, the first step in the synthesis of NAD is the biochemical conversion of niacin to niacinamide, which then forms nicotinamide mononucleotide, an intermediate for NAD formation.

Riboflavin 5-phosphate is the redox co-enzyme FMN, converted in a single step by flavokinase to FAD, which is more frequently used than FMN. Flavokinase is regulated by thyroxin, and in adults hypothyroidism may be associated with riboflavin deficiency. In addition, Bio-3B-G® provides two complete coenzymes, pyridoxal-5-phosphate and thiamine pyrophosphate (also known as cocarboxylase).

Activation of vitamin B6 involves the phosphorylation of pyridoxine (B6) to pyridoxine phosphate, and its subsequent oxidation to the coenzyme pyridoxal 5-phosphate. Bound to albumin, pyridoxal 5-phosphate characterizes a major storage site and transporter for B6. In the serum of healthy persons, Pyridoxal 5-phosphate comprises between 25% and 60% of the circulating levels of vitamin B6.  The liver is the primary site of pyridoxal 5-phosphate formation. Thus it is not surprising that up to 90% of people with cirrhotic liver are deficient in vitamin B6.

Due to the fact that Bio-3B-G® supplies three times the amount of thiamine (“B factor”) in the form of thiamine pyrophosphate and 100% RDA of the B vitamin group, including B2, B3, B6 and B12, it may be a beneficial adjunct in nutritionally supporting normal homoeostatic mechanisms, particularly during stress and/or with elevated blood pressure.

Does not contain: gluten or dairy